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Science 3 August 1979:
Vol. 205. no. 4405, pp. 518 - 520
DOI: 10.1126/science.221984
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Articles

Science, Vol 205, Issue 4405, 518-520
Copyright © 1979 by American Association for the Advancement of Science

articles

6-Hydroxydopamine potentiates acute herpes simplex virus infection of the superior cervical ganglion in mice

RW Price

Treatment of mice with 6-hydroxydopamine increased herpes simplex virus replication in the superior cervical ganglion while it decreased the subsequent prevalence of latent infection. Preganglionic neurectomy failed to block this effect. These observations suggest that intrinsic neural events modify the outcome of viral infections of the nervous system.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)