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Science 20 July 1979:
Vol. 205. no. 4403, pp. 323 - 325
DOI: 10.1126/science.377488
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Articles

Science, Vol 205, Issue 4403, 323-325
Copyright © 1979 by American Association for the Advancement of Science

articles

Cadmium: in vivo measurement in smokers and nonsmokers

KJ Ellis, D Vartsky, I Zanzi, SH Cohn, and S Yasumura

Absolute amounts of cadmium (in milligrams) in the left kidney and concentrations of cadmium (micrograms per gram) in the liver were measured in vivo in 20 healthy adult male volunteers. Organ cadmium levels of smokers were significantly elevated above those of nonsmokers. No relationship was evident between body stores of cadmium (liver and kidney) and cadmium or beta 2-microglobulin in urine or blood. The average total body burden of cadmium in man at age 50 is estimated to be 19.3 milligrams for nonsmokers and 35.5 milligrams for smokers (38.7 pack-year smoking history). Biological half-time for the whole body was, on average, 15.7 years (10- to 33-year range). Dietary absorption was 2.7 micrograms per day. Cigarette smoking resulted in the absorption of 1.9 micrograms per pack.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Urinary cadmium as indicator of renal cadmium in humans: an autopsy study.
C. Orlowski, J. K Piotrowski, J. K Subdys, and A. Gross (1998)
Human and Experimental Toxicology 17, 302-306
   Abstract »    PDF »
Cadmium Concentrations in Human Kidneys from the UK.
R. Scott, E. Aughey, G.S. Fell, and M.J. Quinn (1987)
Human and Experimental Toxicology 6, 111-120
   Abstract »    PDF »
The Uptake by Man of Cadmium Ingested in Crab Meat.
D. Newton, P. Johnson, A.E. Lally, R.J. Pentreath, and D.J. Swift (1984)
Human and Experimental Toxicology 3, 23-28
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)