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ArticlesCopyright © 1979 by American Association for the Advancement of Science
Transmitter-specific retrograde labeling in the striato-nigral and raphe-nigral pathways
Injecting radioactive transmitters into the rat substantia nigra led to retrograde neuronal labeling either in the dorsal raphe nucleus, after 3H-labeled serotonin injection, or in the caudoputamen, after 3H-labeled gamma-aminobutyric acid injection. This differential labeling in projections whose transmitter has been established provides the basis for a histochemical tracing method indicating both connectivity and transmitter specificity of neural pathways.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)