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Science 25 May 1979:
Vol. 204. no. 4395, pp. 877 - 879
DOI: 10.1126/science.220709
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Articles

Science, Vol 204, Issue 4395, 877-879
Copyright © 1979 by American Association for the Advancement of Science

articles

Testosterone reduces refractory period of stria terminalis neurons in the rat brain

KM Kendrick and RF Drewett

The absolute refractory period of neurons projecting from the corticomedial amygdala to the medial preoptic-anterior hypothalamic junction in rats was significantly increased by castration (from 1.01 to 1.61 milliseconds) and decreased again by testosterone (from 1.48 to 0.97 millisecond). Corticomedial amygdala neurons which projected to the capsule of the ventromedial nucleus of the hypothalamus were unaffected. These results demonstrate a specific, direct neuronal effect of testosterone.


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