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Science 25 May 1979:
Vol. 204. no. 4395, pp. 843 - 844
DOI: 10.1126/science.220707
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Articles

Science, Vol 204, Issue 4395, 843-844
Copyright © 1979 by American Association for the Advancement of Science

articles

Beta-adrenergic-sensitive adenylate cyclase in secretory cells of choroid plexus

JA Nathanson

Biochemical evidence supporting the sympathetic control of cerebrospinal fluid production has been obtained through identification of a specific beta-adrenergic-sensitive adenylate cyclase in the choroid plexus. The enzyme, which is localized in the secretory epithelium, is activated by low concentrations of isoproterenol and norepinephrine and appears separate from beta-adrenergic-sensitive adenylate cyclase present in cerebral blood vessels.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Brain barrier tissues: end organs for atriopeptins.
L Steardo and J. Nathanson (1987)
Science 235, 470-473
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Beta-adrenergic-receptor localization by light microscopic autoradiography.
J. Palacios and M. Kuhar (1980)
Science 208, 1378-1380
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