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Science 27 April 1979:
Vol. 204. no. 4391, pp. 432 - 434
DOI: 10.1126/science.312530
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Articles

Science, Vol 204, Issue 4391, 432-434
Copyright © 1979 by American Association for the Advancement of Science

articles

Voltage dependence of junctional conductance in early amphibian embryos

DC Spray, AL Harris, and MV Bennett

Isolated pairs of blastomeres from early amphibian embryos (Ambystoma, Rana, Xenopus) are electrontonically coupled. Junctional conductance and permeability to the dye Lucifer Yellow are markeldy and reversibly decreased by moderate transjunctional polarization in either direction. The relationship between junctional conductance and transjunctional voltage is sufficiently steep that a physiological role in regulation of intercellular communication is plausible.


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