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Science 27 April 1979:
Vol. 204. no. 4391, pp. 417 - 420
DOI: 10.1126/science.35827

Articles

Science, Vol 204, Issue 4391, 417-420
Copyright © 1979 by American Association for the Advancement of Science


articles

Prolonged inhibition of neurons by neuroendocrine cells in Aplysia

P Brownell and E Mayeri

In the abdominal ganglion of Aplysia, a burst of action potentials in peptide-secreting neuroendocrine cells, the bag cells, produces slow inhibition of two identified bursting pacemaker neurons. The inhibition is due to slow hyperpolarizing potential that reduces bursting pacemaker activity for 3 hours or more. The slow inhibitory potential results from a large and prolonged increase in membrane conductance to potassium ions as well as a slower ionic process that is relatively independent of membrane conductance.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Proteolytic processing of the Aplysia egg-laying hormone prohormone.
R. W. Garden, S. A. Shippy, L. Li, T. P. Moroz, and J. V. Sweedler (1998)
PNAS 95, 3972-3977
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Science. ISSN 0036-8075 (print), 1095-9203 (online)