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Science 20 April 1979:
Vol. 204. no. 4390, pp. 318 - 321
DOI: 10.1126/science.219480
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Articles

Science, Vol 204, Issue 4390, 318-321
Copyright © 1979 by American Association for the Advancement of Science

articles

Evolutionary relatedness of viper and primate endogenous retroviruses

PR Andersen, M Barbacid, Tronick SR, HF Clark, and SA Aaronson

A retrovirus previously isolated from a tumored Russell's viper is shown by molecular hybridization to be an endogenous virus of this reptilian species. Radio-immunologic techniques revealed that the viper retrovirus is immunologically and, hence, evolutionarily related to endogenous type D retorviruses of Old World primates. These findings extend the number of vertebrate classes possessing endogenous retroviruses and suggest that type D retroviruses may even be more widely distributed in nature than type C retroviruses.


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