Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 30 March 1979:
Vol. 203. no. 4387, pp. 1349 - 1351
DOI: 10.1126/science.424756
Prev | Table of Contents | Next

Articles

Science, Vol 203, Issue 4387, 1349-1351
Copyright © 1979 by American Association for the Advancement of Science

articles

Sodium-selective liquid ion-exchanger microelectrodes for intracellular measurements

J O'Doherty, JF Garcia-Diaz, and WM Armstrong

The sodium-selective ligand 1,1,1-tris[1(1)-(2(1)-oxa-4(1)-oxo-5(1)-aza-5(1)-methyl)dodecanyl]propane dissolved in 3-nitro-o-xylene containing a small amount of the lipophilic anion tetrachlorophenyl borate was used as a liquid ion-exchanger in sodium-selective microelectrodes. The microelectrodes gave rapid, stable responses that were linear functions of the logarithm of sodium activity. They were tested under conditions approximating those to be expected in the cell interior, and the results indicated that they can be used to measure intracellular sodium activity without significant interference from intracellular potassium.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sodium-coupled sugar transport: effects on intracellular sodium activities and sodium-pump activity.
R. Hudson and S. Schultz (1984)
Science 224, 1237-1239
   Abstract »    PDF »
Calcium regulation during stimulus-secretion coupling: continuous measurement of intracellular calcium activities.
J O'Doherty, S. Youmans, W. Armstrong, and R. Stark (1980)
Science 209, 510-513
   Abstract »    PDF »
Intracellular Ionic Activity Measured in Different Tissues.
M. M. Civan (1980)
JPEN J Parenter Enteral Nutr 4, 131-136
   PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)