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Science 9 February 1979:
Vol. 203. no. 4380, pp. 547 - 548
DOI: 10.1126/science.83676
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Articles

Science, Vol 203, Issue 4380, 547-548
Copyright © 1979 by American Association for the Advancement of Science

articles

Transfer of experimental allergic encephalomyelitis with guinea pig peritoneal exudate cells

BF Driscoll, MW Kies, and EC Alvord Jr

Incubation with specific antigen, myelin basic protein, greatly enhances the ability of guinea pig peritoneal exudate cells to transfer experimental allergic encephalomyelitis. Reproducibly successful transfers are obtained with 10(7) cells. With this relatively small number of cells, in vitro studies to determine the immunologic mechanisms involved in the disease process are now possible.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)