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Science 22 December 1978:
Vol. 202. no. 4374, pp. 1257 - 1260
DOI: 10.1126/science.364651
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Articles

Science, Vol 202, Issue 4374, 1257-1260
Copyright © 1978 by American Association for the Advancement of Science

articles

Implications of RNA-RNA splicing in evolution of eukaryotic cells

JE Darnell Jr

The differences in the biochemistry of messenger RNA formation in eukaryotes compared to prokaryotes are so profound as to suggest that sequential prokaryotic to eukaryotic cell evolution seems unlikely. The recently discovered noncontiguous sequences in eukaryotic DNA that encode messenger RNA may reflect an ancient, rather than a new, distribution of information in DNA and that eukaryotes evolved independently of prokaryotes.


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