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Science 1 December 1978:
Vol. 202. no. 4371, pp. 977 - 979
DOI: 10.1126/science.309655
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Articles

Science, Vol 202, Issue 4371, 977-979
Copyright © 1978 by American Association for the Advancement of Science

articles

Serotonin shifts the phase of the circadian rhythm from the Aplysia eye

G Corrent, DJ McAdoo, and A Eskin

A putative neurotransmitter, serotonin, may be used to transmit temporal information in the eye of Aplysia, because it can shift the phase of the circadian rhythm of spontaneous optic nerve impulses from the eye and the eye contains a significant quantity of serotonin. Serotonin acts either directly on the cell, or cells, containing the circadian pacemaker or on cells electronically coupled to the pacemaker cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Translational and Transcriptional Inhibitors Block Serotonergic Phase Advances of the Suprachiasmatic Nucleus Circadian Pacemaker In Vitro.
A. Jovanovska and R. A. Prosser (2002)
J Biol Rhythms 17, 137-146
   Abstract »    PDF »
Ionic Currents of Isolated Retinal Pacemaker Neurons: Projected Daily Phase Differences and Selective Enhancement by a Phase-Shifting Neurotransmitter.
S. Barnes and J. W. Jacklet (1997)
J Neurophysiol 77, 3075-3084
   Abstract »    Full Text »    PDF »
Serotonin and the Mammalian Circadian System: I. In Vitro Phase Shifts by Serotonergic Agonists and Antagonists.
R. A. Prosser, R. R. Dean, D. M. Edgar, H. C. Heller, and J. D. Miller (1993)
J Biol Rhythms 8, 1-16
   Abstract »    PDF »
Serotonin Phase-Shifts the Circadian Rhythm of Locomotor Activity in the Cockroach.
T. L. Page (1987)
J Biol Rhythms 2, 23-34
   Abstract »    PDF »
Cellular Analysis of Ocular Circadian Pacemaker Coupling in Bulla: Role of Efferent Impulses in Phase Shifting.
G. D. Block, M. H. Roberts, and A. E. Lusska (1986)
J Biol Rhythms 1, 199-217
   Abstract »    PDF »
Adenylate cyclase activation shifts the phase of a circadian pacemaker.
A Eskin and J. Takahashi (1983)
Science 220, 82-84
   Abstract »    PDF »
Regulation of circadian rhythmicity.
J. Takahashi and M Zatz (1982)
Science 217, 1104-1111
   Abstract »    PDF »
Intraventricular carbachol mimics the effects of light on the circadian rhythm in the rat pineal gland.
M Zatz and M. Brownstein (1979)
Science 203, 358-361
   Abstract »    PDF »


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