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Science 27 October 1978:
Vol. 202. no. 4366, pp. 438 - 440
DOI: 10.1126/science.705337
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Articles

Science, Vol 202, Issue 4366, 438-440
Copyright © 1978 by American Association for the Advancement of Science

articles

Hepatic fibrosis in schistosomiasis: egg granulomas secrete fibroblast stimulating factor in vitro

DJ Wyler, SM Wahl, and LM Wahl

Cytosol extracts and culture supernatants of isolated egg granulomas obtained from livers of mice with Schistosoma mansoni infection stimulated fibroblasts to incorporate tritiated thymidine and to proliferate in vitro. This finding suggests that hepatic granulomas may play a role in regulating hepatic fibrosis in Schistosoma mansoni infections.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Schistosome Infections in Humans: Perspectives and Recent Findings.
T. E. NASH, A. W. CHEEVER, E. A. OTTESEN, and J. A. COOK (1982)
Ann Intern Med 97, 740-754
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Science. ISSN 0036-8075 (print), 1095-9203 (online)