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Science 20 October 1978:
Vol. 202. no. 4365, pp. 311 - 313
DOI: 10.1126/science.694535

Articles

Science, Vol 202, Issue 4365, 311-313
Copyright © 1978 by American Association for the Advancement of Science


articles

Prolactin synthesis by human chorion-decidual tissue: a possible source of prolactin in the amniotic fluid

A Golander, T Hurley, J Barrett, A Hizi, and S Handwerger

Explants of human chorion-decidual tissue obtained at delivery from normal, full-term pregnancies synthesize and secrete prolactin. This hormone is indistinguishable from pituitary prolactin by chromatographic, electrophoretic, immunologic, and receptor assay techniques. These results suggest that chorion-decidua may be the source of the large quantities of prolactin in amniotic fluid.


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What Can We Learn from Rodents about Prolactin in Humans?.
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Autocrine Prolactin Inhibits Human Uterine Decidualization: A Novel Role for Prolactin.
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The Molecular Control of Corpus Luteum Formation, Function, and Regression.
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LS14: A Novel Human Adipocyte Cell Line that Produces Prolactin.
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Pituitary Hypoplasia and Lactotroph Dysfunction in Mice Deficient for Cyclin-Dependent Kinase-4.
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Intact Follicular Maturation and Defective Luteal Function in Mice Deficient for Cyclin- Dependent Kinase-4.
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Rat Decidual Prolactin. IDENTIFICATION, MOLECULAR CLONING, AND CHARACTERIZATION.
A. Prigent-Tessier, C. Tessier, M. Hirosawa-Takamori, C. Boyer, S. Ferguson-Gottschall, and G. Gibori (1999)
J. Biol. Chem. 274, 37982-37989
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Localization of Interferon Regulatory Factor-1 (IRF-1) in Nonpregnant Human Endometrium: Expression of IRF-1 Is Up-Regulated by Prolactin during the Secretory Phase of the Menstrual Cycle.
H. N. Jabbour, H. O. D. Critchley, L.-y. Yu-Lee, and S. C. Boddy (1999)
J. Clin. Endocrinol. Metab. 84, 4260-4265
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Expression of Functional Prolactin Receptors in Nonpregnant Human Endometrium: Janus Kinase-2, Signal Transducer and Activator of Transcription-1 (STAT1), and STAT5 Proteins Are Phosphorylated after Stimulation with Prolactin.
H. N. Jabbour, H. O. D. Critchley, and S. C. Boddy (1998)
J. Clin. Endocrinol. Metab. 83, 2545-2553
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Dimeric Inhibins in Amniotic Fluid, Maternal Serum, and Fetal Serum in Human Pregnancy.
E. M. Wallace, S. C. Riley, J. A. Crossley, S. C. Ritoe, A. Horne, M. Shade, P. M. Ellis, D. A. Aitken, and N. P. Groome (1997)
J. Clin. Endocrinol. Metab. 82, 218-222
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