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Science 13 October 1978:
Vol. 202. no. 4364, pp. 221 - 223
DOI: 10.1126/science.211585
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Articles

Science, Vol 202, Issue 4364, 221-223
Copyright © 1978 by American Association for the Advancement of Science

articles

beta-Endorphin is not detectable in plasma from normal human subjects

T Suda, AS Liotta, and DT Krieger

beta-Endorphin is not detectable in plasma from normal human subjects when measured under baseline conditions or after the subjects have received vasopressin, an agent that elevates beta-lipotropin and adrenocorticotropic hormone (ACTH). Significant amounts of beta-endorphin are present in plasma of patients with endocrine disorders associated with increased ACTH and beta-lipotropin production. Highly purified, natural beta-lipotropin is not peripherally converted to beta-endorphin in vivo in normal subjects.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Corticotropin-Releasing Factor Up-Regulates Its Own Receptor Gene Expression in Corticotropic Adenoma Cells in Vitro.
Y. Sakai, N. Horiba, K. Sakai, F. Tozawa, A. Kuwayama, H. Demura, and T. Suda (1997)
J. Clin. Endocrinol. Metab. 82, 1229-1234
   Abstract »    Full Text »    PDF »
Neuropsychiatric Manifestations of Patients With Cushing's Syndrome: Relationship to Cortisol and Adrenocorticotropic Hormone Levels.
M. N. Starkman and D. E. Schteingart (1981)
Arch Intern Med 141, 215-219
   Abstract »    PDF »
Plasma beta-endorphin immunoreactivity in schizophrenia.
M Ross, P. Berger, and A Goldstein (1979)
Science 205, 1163-1164
   Abstract »    PDF »
Specific nonopiate receptors for beta-endorphin.
E Hazum, K. Chang, and P Cuatrecasas (1979)
Science 205, 1033-1035
   Abstract »    PDF »
Pituitary hormones in brain: where, how, and why?.
D. Krieger and A. Liotta (1979)
Science 205, 366-372
   Abstract »    PDF »
The Cushing Syndromes: Changing Views of Diagnosis and Treatment.
E. M. GOLD (1979)
Ann Intern Med 90, 829-844
   Abstract »    PDF »


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