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Science 15 September 1978:
Vol. 201. no. 4360, pp. 1020 - 1023
DOI: 10.1126/science.684422
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Articles

Science, Vol 201, Issue 4360, 1020-1023
Copyright © 1978 by American Association for the Advancement of Science

articles

Children absorb tris-BP flame retardant from sleepwear: urine contains the mutagenic metabolite, 2,3-dibromopropanol

A Blum, MD Gold, BN Ames, FR Jones, EA Hett, RC Dougherty, EC Horning, I Dzidic, DI Carroll, RN Stillwell, and JP Thenot

The flame retardant, tris(2,3-dibromopropyl)phosphate (tris-BP), which is a mutagen and causes cancer and sterility in animals is absorbed from fabric by people. 2,3-Dibromopropanol, a metboloite of tris-BP and a mutagen itself, has been found in the urine samples of ten children who were wearing or who had worn tris-BP-treated sleepwear. Eight of these children were wearing well-washed sleepwear and the possibility of absorption of tris-BP from well-washed sleepwear discussed. 2,3-Dibromopropanol was not found in the urines of one child and one adult who had never worn tris-BP-treated garments.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Chronic Toxicity and Carcinogenic Potential of Tris-(1,3-Dichloro-2-propyl) Phosphate in Sprague-Dawley Rat.
R. I. Freudenthal and R. T. Henrich (2000)
International Journal of Toxicology 19, 119-125
   Abstract »    PDF »
Mitogenesis is only one factor in carcinogenesis.
I. Weinstein (1991)
Science 251, 387-388
   PDF »
Tris(dichloropropyl)phosphate, a mutagenic flame retardant: frequent cocurrence in human seminal plasma.
T Hudec, J Thean, D Kuehl, and R. Dougherty (1981)
Science 211, 951-952
   Abstract »    PDF »
Identifying environmental chemicals causing mutations and cancer.
B. Ames (1979)
Science 204, 587-593
   Abstract »    PDF »
Computer Science: Surprisingly Fast Algorithms.
G. B. KOLATA (1978)
Science 202, 857-858
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