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Science 8 September 1978:
Vol. 201. no. 4359, pp. 937 - 938
DOI: 10.1126/science.356266
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Articles

Science, Vol 201, Issue 4359, 937-938
Copyright © 1978 by American Association for the Advancement of Science

articles

Bone marrow origin of hepatic macrophages (Kupffer cells) in humans

RP Gale, RS Sparkes, and DW Golde

Hepatic macrophages (Kupffer cells) from two male recipients of bone marrow transplants from females were studied for fluorescent Y body staining and sex chromatin (Barr body). After the transplant, macrophages had the sex karyotype of the donor, indicating that human hepatic macrophages originate in bone marrow.


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