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Science 8 September 1978: Vol. 201. no. 4359, pp. 875 - 880 DOI: 10.1126/science.210504
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Articles
Science, Vol 201, Issue 4359, 875-880
Copyright © 1978 by American Association for the Advancement of Science
The biology of oxygen radicals
I Fridovich
The reactive superoxide radical, O2-, formerly of concern only to radiation chemists and radiobiologists, is now understood to be a normal product of the biological reduction of molecular oxygen. An unusual family of enzymes, the superoxide dismutases, protect against the deleterious actions of this radical by catalyzing its dismutation to hydrogen peroxide plus oxygen.
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- Antioxidant enzymes, inflammatory indices and lifestyle factors in older men: a cohort analysis.
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QJM
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- Eicosapentaenoic Acid and Docosahexaenoic Acid Block Serotonin-Induced Smooth Muscle Cell Proliferation.
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19, 2316-2322
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- Nitric Oxide Enhances the Manganese Superoxide Dismutase-dependent Suppression of Proliferation in HT-1080 Fibrosarcoma Cells.
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- Reactive Oxygen Species Mediate Activity-Dependent Neuron-Glia Signaling in Output Fibers of the Hippocampus.
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- Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells.
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Am J Physiol Lung Cell Mol Physiol
277, L589-L595
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- Characterization of the Major Superoxide Dismutase of Staphylococcus aureus and Its Role in Starvation Survival, Stress Resistance, and Pathogenicity.
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- Mass spectrometric quantification of amino acid oxidation products in proteins: insights into pathways that promote LDL oxidation in the human artery wall.
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FASEB J
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- Regulation of lung manganese superoxide dismutase: species variation in response to lipopolysaccharide.
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Am J Physiol Lung Cell Mol Physiol
276, L705-L708
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- The bspA Locus of Lactobacillus fermentum BR11 Encodes an L-Cystine Uptake System.
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- Inhibition of copper/zinc superoxide dismutase impairs NO ·-mediated endothelium-dependent relaxations.
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Am J Physiol Heart Circ Physiol
276, H1043-H1048
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- JunB Forms the Majority of the AP-1 Complex and Is a Target for Redox Regulation by Receptor Tyrosine Kinase and G Protein-coupled Receptor Agonists in Smooth Muscle Cells.
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- A New Antioxidant with Alkyl Hydroperoxide Defense Properties in Yeast.
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- Gene Transfer of Mitochondrially Targeted Glutathione Reductase Protects H441 Cells from t-Butyl Hydroperoxide-Induced Oxidant Stresses.
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- Bicarbonate Is Required for the Peroxidase Function of Cu,Zn-Superoxide Dismutase at Physiological pH.
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- A Mechanism of Resistance to Hydrogen Peroxide in Vibrio rumoiensis S-1.
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