Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Science Careers Booklet

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 28 July 1978:
Vol. 201. no. 4353, pp. 358 - 360
DOI: 10.1126/science.663662
Prev | Table of Contents | Next

Articles

Science, Vol 201, Issue 4353, 358-360
Copyright © 1978 by American Association for the Advancement of Science

articles

Brain edema: induction in cortical slices by polyunsaturated fatty acids

PH Chan and RA Fishman

The presence of polyunsaturated and saturated fatty acids in leukocytic membranes prompted study of their possible role in the induction of brain edema. Polyunsaturated fatty acids including sodium arachidonate, sodium linoleate, sodium linolenate, and docasahexaenoic acids induced edma in slices of rat brain cortex. This cellular edema was specific, since neither saturated fatty acids nor a fatty acid containing a single double bond had such effect.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Effects of Fluid Management on Edema Volume and Midline Shift in a Rat Model of Ischemic Stroke Editorial Comment.
R. P. Paczynski, R. Venkatesan, M. N. Diringer, Y. Y. He, C. Y. Hsu, W. Lin, and P. H. Chan (2000)
Stroke 31, 1702-1708
   Abstract »    Full Text »    PDF »
Swelling-Induced Arachidonic Acid Release via the 85-kDa cPLA2 in Human Neuroblastoma Cells.
S. Basavappa, S. F. Pedersen, N. K. Jorgensen, J. C. Ellory, and E. K. Hoffmann (1998)
J Neurophysiol 79, 1441-1449
   Abstract »    Full Text »    PDF »
Functional Significance of Cell Volume Regulatory Mechanisms.
F. LANG, G. L. BUSCH, M. RITTER, H. VOLKL, S. WALDEGGER, E. GULBINS, and D. HAUSSINGER (1998)
Physiol Rev 78, 247-306
   Abstract »    Full Text »    PDF »


ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)