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Science 16 June 1978:
Vol. 200. no. 4347, pp. 1292 - 1295
DOI: 10.1126/science.78522
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Articles

Science, Vol 200, Issue 4347, 1292-1295
Copyright © 1978 by American Association for the Advancement of Science

articles

Substances moved by axonal transport and released by nerve stimulation have an innervation-like effect on muscle

SG Younkin, RS Brett, B Davey, and L Younkin

Substances which have an innervation-like effect on the cholinesterase activity of organ-cultured rat extensor digitorum longus muscles are moved in nerve by axonal transport, are released from nerve by stimulation, and are present in innervated muscle but apparently absent from denervated muscle. Substances which increase the acetylcholine sensitivity of cultured muscles behave similarly.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)