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Science 9 June 1978:
Vol. 200. no. 4346, pp. 1163 - 1165
DOI: 10.1126/science.206965
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Articles

Science, Vol 200, Issue 4346, 1163-1165
Copyright © 1978 by American Association for the Advancement of Science

articles

Absence of adenosine deaminase activity in a mammalian cell line transformed by Rous sarcoma virus

C Shipman Jr and JC Drach

No detectable adenosine deaminase activity was found in whole cells or 105,000g cytosol preparations of B-mix K-44/6 cells when either [3H]adenosine or [3H]arabinosyladenine was used as substrate. When grown in tissue culture medium supplemented with horse serum these cells provide a deaminase-free system not requiring the use of an adenosine deaminase inhibitor.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB.
S. Wiese, S. Jablonka, B. Holtmann, N. Orel, R. Rajagopal, M. V. Chao, and M. Sendtner (2007)
PNAS 104, 17210-17215
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Science. ISSN 0036-8075 (print), 1095-9203 (online)