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Science 26 May 1978:
Vol. 200. no. 4344, pp. 952 - 958
DOI: 10.1126/science.77042
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Articles

Science, Vol 200, Issue 4344, 952-958
Copyright © 1978 by American Association for the Advancement of Science

articles

Prenatal diagnosis of genetic disorders

GS Omenn

Sampling of amniotic fluid, visualization of the fetus, fetal blood sampling, and screening of maternal blood represent successive approaches to the diagnosis of specific genetic disorders in the second trimester of pregnancy. Clinical and ethical concerns about the appropriateness, safety, and efficacy of the techniques have led to multidisciplinary assessments at an early stage. A major growth in demand for medical and educational genetic services can be anticipated.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)