Science, Vol 200, Issue 4339, 320-321
Copyright © 1978 by American Association for the Advancement of Science
Rejection of male skin grafts by splenectomized female mice
TA Coons
and
EH Goldberg
Female mice of the C3H strain normally do not reject skin grafts from males of the same strain; however, 40 percent of splenectomized C3H female mice completely rejected C3H male skin grafts applied 2 weeks later. All splenectomized females showed at least transitory signs of graft rejection.