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Science 14 April 1978:
Vol. 200. no. 4338, pp. 211 - 213
DOI: 10.1126/science.24895
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Articles

Science, Vol 200, Issue 4338, 211-213
Copyright © 1978 by American Association for the Advancement of Science

articles

Oral cocaine: plasma concentrations and central effects

C Van Dyke, P Jatlow, J Ungerer, PG Barash, and R Byck

Cocaine (2.0 milligrams per kilogram) given by the oral route is at least as effective as the same dose given intranasally. Cocaine is not detected in the plasma until 30 minutes after oral administration, but peak plasma concentrations are similar after both routes. The subjective "highs" in man are greater after oral than after intranasal administration.


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Death Caused by Recreational Cocaine Use.
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