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Science 3 March 1978:
Vol. 199. no. 4332, pp. 988 - 990
DOI: 10.1126/science.622581
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Articles

Science, Vol 199, Issue 4332, 988-990
Copyright © 1978 by American Association for the Advancement of Science

articles

Contact-mediated bone resorption by human monocytes in vitro

AJ Kahn, CC Stewart, and SL Teitelbaum

Human circulating monocytes in tissue culture are capable of resorbing devitalized adult and fetal bone. An important component of this process is the adhesion of the cells to the mineralized substrate and the localized removal of matrix from beneath the attached cells. The process appears to involve both release of lysosomal enzymes onto the substrate and intracellular accumulation (transport) of resorbed matrix.


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Current Concepts Review - Cellular Biology of Bone-Resorbing Cells.
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Morphologic Development of Experimental Cholesteatoma.
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Cellular Roles in Physiological Root Resorption of Deciduous Teeth in the Cat.
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Journal of Dental Research 69, 67-74
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Effects of Culture Supernatants of Leukocytes from Periodontal Patients on Monocyte-Mediated Hydroxyapatite Resorption.
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Advances in Dental Research 2, 368-371
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The Histiocytic Disorders: A Pathophysiologic Analysis.
J. E. GROOPMAN and D. W. GOLDE (1981)
Ann Intern Med 94, 95-107
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