Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 3 March 1978:
Vol. 199. no. 4332, pp. 978 - 980
DOI: 10.1126/science.199.4332.978
Prev | Table of Contents | Next

Articles

Alkaloids in Whole Plant Material: Direct Analysis by Kinetic Energy Spectrometry

R. W. KONDRAT 1, R. G. COOKS 1, and J. L. McLAUGHLIN 2

1 Department of Chemistry, Purdue University, West Lafayette, Indiana 47907
2 Department of Medicinal Chemistry and Pharmacognosy, Purdue University

A new approach to mixture analysis has been applied to the direct detection of various alkaloids in plant materials. The method requires absolutely no sample treatment. Results are presented for cocaine, morphine, papaverine, coniine, and atropine. The signal-to-background characteristics are superior to those of conventional mass spectrometry. Sensitivity is sufficient to detect and identify between 1 and 10 nanograms of alkaloid.

Submitted on August 15, 1977
Revised on November 18, 1977


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Modified bases characterized in intact DNA by mass-analyzed ion kinetic energy spectrometry.
A. Schoen, R. Cooks, and J. Wiebers (1979)
Science 203, 1249-1251
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)