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Science 3 February 1978:
Vol. 199. no. 4328, pp. 545 - 547
DOI: 10.1126/science.622555
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Articles

Science, Vol 199, Issue 4328, 545-547
Copyright © 1978 by American Association for the Advancement of Science

articles

Lichen myxedematosus serum stimulates human skin fibroblast proliferation

RA Harper and J Rispler

Serum from patients with lichen myxedematosus, when added to exponentially growing normal human skin fibroblasts, stimulates DNA synthesis and cell proliferation. The degree of response in vitro is correlated with the extent of the disease in vivo and is specific for fibroblasts. The results suggest that there is a systemic factor (or factors) which may play a role in the etiology of diseases affecting the connective tissue.


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Scleromyxedema: role of high-dose melphalan with autologous stem cell transplantation.
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Successful Treatment of Scleromyxedema With Autologous Peripheral Blood Stem Cell Transplantation.
M. Q. Lacy, W. J. Hogan, M. A. Gertz, A. Dispenzieri, S. V. Rajkumar, S. Hayman, S. Kumar, M. R. Litzow, and A. L. Schroeter (2005)
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Thalidomide as a Potential Treatment for Scleromyxedema.
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Arch Dermatol 140, 277-280
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Resident's Page.
(1981)
Arch Dermatol 117, 440-442
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Treatment of Scleromyxedema With Melphalan.
R. B. Harris, H. O. Perry, R. A. Kyle, and R. K. Winkelmann (1979)
Arch Dermatol 115, 295-299
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