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Science 13 January 1978:
Vol. 199. no. 4325, pp. 199 - 200
DOI: 10.1126/science.413192
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Articles

Science, Vol 199, Issue 4325, 199-200
Copyright © 1978 by American Association for the Advancement of Science

articles

Environmental hydrocarbons produce degeneration in cat hypothalamus and optic tract

HH Schaumburg and PS Spencer

2,5-Hexanedione, the principal neurotoxic metabolite of the industrial solvents n-hexane and methyl n-butyl ketone causes axonal degeneration in the mammillary body and visual nuclei of cats. Prolonged, low-level exposure to hydrocarbons in the environment may cause premature deterioration in areas of the human brain vital for perception and behavior.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Colour vision defects in occupational chronic solvent encephalopathy.
J. Paallysaho, R. Nasanen, M. Mantyjarvi, A. Kaukiainen, and M. Sainio (2007)
Human and Experimental Toxicology 26, 375-384
   Abstract »    PDF »
Subchronic Inhalation Toxicity of Two Motor Fuels.
R. A. Kuna and C. E. Ulrich (1984)
International Journal of Toxicology 3, 217-229
   Abstract »    PDF »


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