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Science 6 January 1978:
Vol. 199. no. 4324, pp. 83 - 84
DOI: 10.1126/science.199.4324.83
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Articles

Melatonin Content of the Human Pineal Gland

A. C. GREINER 1 and S. C. CHAN 2

1 North Lawn Unit, Riverview Hospital, Essondale, British Columbia, Canada VOM 1J0
2 North Lawn Unit, Riverview Hospital, and Department of Chemistry, University of British Columbia, Vancouver

Gas chromatography with electron capture detection was used to quantitate melatonin in single human pineal glands. The sensitivity of this melatonin assay is in the low picogram range. A 24-hour rhythm of pineal melatonin content was observed.

Submitted on September 12, 1977


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Analysis of melatonin in human plasma by gas chromatography negative chemical ionization mass spectrometry.
A. Lewy and S. Markey (1978)
Science 201, 741-743
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Science. ISSN 0036-8075 (print), 1095-9203 (online)