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Science 23 December 1977:
Vol. 198. no. 4323, pp. 1271 - 1274
DOI: 10.1126/science.929200
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Articles

Science, Vol 198, Issue 4323, 1271-1274
Copyright © 1977 by American Association for the Advancement of Science

articles

Body weight: reduction by long-term glycerol treatment

D Wirtshafter and JD Davis

Elevation of body glycerol concentration by multiple daily injections of glycerol was shown to lead to hypophagia and body weight loss followed by normal food intake and normal rate of body weight increase in rats. Termination of injections was followed by hyperphagia and an accelerated rate of growth. These findings suggest that the blood glycerol concentration plays an important role in the control of body weight and may be one signal by which the central nervous system monitors body lipid content.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats.
J. Davis, D Wirtshafter, K. Asin, and D Brief (1981)
Science 212, 81-83
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Science. ISSN 0036-8075 (print), 1095-9203 (online)