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Science 23 December 1977:
Vol. 198. no. 4323, pp. 1269 - 1271
DOI: 10.1126/science.201028
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Articles

Science, Vol 198, Issue 4323, 1269-1271
Copyright © 1977 by American Association for the Advancement of Science

articles

Structural basis for on-and off-center responses in retinal bipolar cells

WK Stell, AT Ishida, and DO Lightfoot

Electron microscopy of Golgi preparations of goldfish retina shows that dendrites of type a (hyperpolarizing, off-center) bipolar cells make wide cleft junctions unassociated with synaptic ribbons, while those of type b (depolarizing, on-center) bioplar cells make narrow cleft junctions and synaptic ribbon contacts, with rods and cones. This suggests that wide cleft junctions are the site of sign-conserving, and narrow cleft junctions or ribbon contacts (or both) are the site of sign-inverting synaptic transmission from photoreceptors to bipolars.


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A Novel Connection between Rods and ON Cone Bipolar Cells Revealed by Ectopic Metabotropic Glutamate Receptor 7 (mGluR7) in mGluR6-Deficient Mouse Retinas.
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Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina.
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Retinal Bipolar Cell Input Mechanisms in Giant Danio. III. ON-OFF Bipolar Cells and Their Color-Opponent Mechanisms.
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Microcircuits for Night Vision in Mouse Retina.
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Synapse Formation Is Arrested in Retinal Photoreceptors of the Zebrafish nrc Mutant.
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Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells.
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Glutamate Responses of Bipolar Cells in a Slice Preparation of the Rat Retina.
T. Euler, H. Schneider, and H. Wassle (1996)
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Neuronal architecture of on and off pathways to ganglion cells in carp retina.
E. Famiglietti Jr, A Kaneko, and M Tachibana (1977)
Science 198, 1267-1269
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