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Science 2 September 1977:
Vol. 197. no. 4307, pp. 1010 - 1012
DOI: 10.1126/science.887936
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Articles

Science, Vol 197, Issue 4307, 1010-1012
Copyright © 1977 by American Association for the Advancement of Science

articles

Phase separation of a protein-water mixture in cold cataract in the young rat lens

T Tanaka, C Ishimoto, and LT Chylack Jr

A remarkable resemblance between the appearance of opacity in lysozyme--salt water mixtures and the development of opacity in cold cataract in the young rat lens is strong evidence that cold cataract is fundamentally a phase separation of the "protein-water binary mixture" in the lens.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Molecular basis of a progressive juvenile-onset hereditary cataract.
A. Pande, J. Pande, N. Asherie, A. Lomakin, O. Ogun, J. A. King, N. H. Lubsen, D. Walton, and G. B. Benedek (2000)
PNAS 97, 1993-1998
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Science. ISSN 0036-8075 (print), 1095-9203 (online)