Science, Vol 197, Issue 4304, 659-660
Copyright © 1977 by American Association for the Advancement of Science
Porphyrin induction: equivalent effects of 5alphaH and 5betaH steroids in chick embryo liver cells
JK Stephens,
PW Fischer,
and
GS Marks
The 5alphaH (A : B trans) and 5betaH (A : B cis) steroids are equipotent in inducing delta-aminolevulinic acid synthetase and porphyrin accumulation in chick embryo liver cells maintained in serum-free culture medium. Thus there is no specific steric requirement for porphyrin-inducing activity in steroids.