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Science 5 August 1977:
Vol. 197. no. 4303, pp. 571 - 573
DOI: 10.1126/science.267328
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Articles

Science, Vol 197, Issue 4303, 571-573
Copyright © 1977 by American Association for the Advancement of Science

articles

Host control of tumor growth

CC Ting, SC Tsai, and MJ Rogers

A humoral factor (molecular weight less than 60,000) that was present in the ascitic fluid of mice bearing intraperitoneal tumors and in pleural effusions from human cancer patients was found to promote the growth of a murine tumor and to suppress cell-mediated tumor immunity. However, the hosts that had recovered from the immunosuppressive state produced a serum factor that could neutralize the immunosuppressive effect.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)