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Science 8 July 1977:
Vol. 197. no. 4299, pp. 179 - 180
DOI: 10.1126/science.197.4299.179

Articles

Pineal Vasotocin: Release into Cat Cerebrospinal Fluid by Melanocyte-Stimulating Hormone Release-Inhibiting Factor

S. PAVEL 1, R. GOLDSTEIN 1, CARMEN GHEORGHIU 1, and MARIA CALB 1

1 Institute of Endocrinology, Bucharest, Rumania

The intracarotid injection of both synthetic melanocyte-stimulating hormone release-inhibiting factor (MIF) and purified MIF prepared from bovine hypothalami induces arginine vasotocin release into cerebrospinal fluid of cats and significantly decreases the pineal arginine vasotocin content at 5 minutes after the injection. The present results demonstrate an extrapituitary endocrine effect of synthetic and purified bovine MIF.

Submitted on December 13, 1976





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Science. ISSN 0036-8075 (print), 1095-9203 (online)