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Science 8 July 1977:
Vol. 197. no. 4299, pp. 169 - 171
DOI: 10.1126/science.877548
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Articles

Science, Vol 197, Issue 4299, 169-171
Copyright © 1977 by American Association for the Advancement of Science

articles

Transport interaction of cystine and dibasic amino acids in renal brush border vesicles

S Segal, PD McNamara, and LM Pepe

The uptake of cystine by vesicles prepared from rat kidney brush borders occurs by two distinct transport systems. The higher affinity system is inhibited by the dibasic amino acids lysine, arginine, and ornithine. The lower affinity system, unaffected by dibasic amino acids, appears to correspond to that observed by studying uptake of cystine by kidney slices.


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