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Science 17 June 1977:
Vol. 196. no. 4296, pp. 1334 - 1336
DOI: 10.1126/science.867032
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Articles

Science, Vol 196, Issue 4296, 1334-1336
Copyright © 1977 by American Association for the Advancement of Science

articles

Radioimmunoassay for abnormal hemoglobins

FA Garver, MB Baker, CS Jones, M Gravely, G Altay, and TH Huisman

A sensitive and specific radioimmunoassay has been developed for the identification or quantification of the human hemoglobin variants S, C, D-Los Angeles, E, G Philadelphia, Russ, O Arab, Beograd, J Paris I, G San Jose, Q Iran, Korle Bu, and F Malta I. In the immunoassay, monospecific antibody preparations are used which recognize the single amino acid substitution in the variant polypeptide chail and do not cross-react with normal hemoglobins or hemoglobin variants containing a different amino acid exchange at the same position.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Depletion of Serum Hemopexin in Fulminant Rhabdomyolysis: Evidence for an Interaction of Hemopexin With Myoglobin-Derived Heme.
B. T. Adornato, L. J. Kagen, F. A. Garver, and W. K. Engel (1978)
Arch Neurol 35, 547-548
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