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Science 10 June 1977:
Vol. 196. no. 4295, pp. 1213 - 1214
DOI: 10.1126/science.860136
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Articles

Science, Vol 196, Issue 4295, 1213-1214
Copyright © 1977 by American Association for the Advancement of Science

articles

Stability of the individual globin genes during erythroid differentiation

E Benz Jr, P Turner, J Barker, and A Nienhuis

The genes of sheep betaA, betaC, and gamma globin were all present in DNA from erythroid cells which synthesized only betaC globin. Similarly, selective excision of non-expressed genes was shown not to occur during human erythroid differentiation. In contrast, evolutionary deletion of the betaC gene accounts for the inability of many sheep to make this globin.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)