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Science 10 June 1977:
Vol. 196. no. 4295, pp. 1211 - 1213
DOI: 10.1126/science.860135
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Articles

Science, Vol 196, Issue 4295, 1211-1213
Copyright © 1977 by American Association for the Advancement of Science

articles

Insecticide solvents: interference with insecticidal action

LB Brattsten and CF Wilkinson

Several commercial solvent mixtures commonly used as insecticide carriers in spray formulations increase by more than threefold the microsomal N-demethylation of p-chloro N-methylaniline in midgut preparations of southern army-worm (Spodoptera eridania) larvae exposed orally to the test solvents. Under laboratory conditions, the same solvent mixtures exhibit a protective action against the in vivo toxicity of the insecticide carbaryl to the larvae. The data are discussed with respect to possible solvent-insecticide interactions occurring under field conditions and, more broadly, to potential toxicological hazards of these solvents to humans.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Insecticide Resistance: Challenge to Pest Management and Basic Research.
L. B. BRATTSTEN, C. W. HOLYOKE JR., J. R. LEEPER, and K. F. RAFFA (1986)
Science 231, 1255-1260
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Specialization: Species Property or Local Phenomenon?.
L. R. Fox and P. A. Morrow (1981)
Science 211, 887-893
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Herbivore-Plant Interactions: Mixed-Function Oxidases and Secondary Plant Substances.
L. B. BRATTSTEN, C. F. WILKINSON, and T. EISNER (1977)
Science 196, 1349-1352
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