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Science 3 June 1977:
Vol. 196. no. 4294, pp. 1106 - 1109
DOI: 10.1126/science.860132

Articles

Science, Vol 196, Issue 4294, 1106-1109
Copyright © 1977 by American Association for the Advancement of Science


articles

Nuclear morphometry during the cell cycle

F Kendall, R Swenson, T Borun, J Rowinski, and C Nicolini

Directly measured and derived geometric and densitometric parameters were obtained by means of the automated image analyzer Quantimet 720-D in Feulgen-stained HeLa cells synchronized by selective mitotic detachment. These data indicate substantial alteration of nuclear morphology during the entire cell cycle, even during the G1 and G2 phases, and the late G1-early S and late S-G2 transitions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
High-content imaging characterization of cell cycle therapeutics through in vitro and in vivo subpopulation analysis.
J. Low, S. Huang, W. Blosser, M. Dowless, J. Burch, B. Neubauer, and L. Stancato (2008)
Mol. Cancer Ther. 7, 2455-2463
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Science. ISSN 0036-8075 (print), 1095-9203 (online)