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Science 27 May 1977:
Vol. 196. no. 4293, pp. 995 - 998
DOI: 10.1126/science.193191
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Articles

Science, Vol 196, Issue 4293, 995-998
Copyright © 1977 by American Association for the Advancement of Science

articles

Synapse formation between two clonal cell lines

CN Christian, PG Nelson, J Peacock, and M Nirenberg

Clonal neuroblastoma x glioma hybrid cells frequently formed synapses with clonal mouse striated muscle cells. Clonal myotubes were similar to cultured mouse embryo myotubes with respect to acetylcholine sensitivity and other membrane properties examined. However, acetylcholine sensitivity measurements indicate that acetylcholine receptors of clonal myotubes are distributed more uniformly over the cell surface than the receptors of cultured mouse embryo myotubes.


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