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Science 6 May 1977:
Vol. 196. no. 4290, pp. 660 - 662
DOI: 10.1126/science.404705
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Articles

Science, Vol 196, Issue 4290, 660-662
Copyright © 1977 by American Association for the Advancement of Science

articles

Thyrotropin-releasing hormone: stimulation of colonic activity following intracerebroventricular administration

Smith JR, TR La Hann, RM Chesnut, MA Carino, and A Horita

Intraventricularly administered thyrotropin-releasing hormone in rabbits elicited an increase in intraluminal pressure changes, a response commonly associated with muscular activity of the colon. The response appears to be central in origin with peripheral expression relying primarily on cholinergic receptors.


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