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Science 6 May 1977:
Vol. 196. no. 4290, pp. 655 - 656
DOI: 10.1126/science.854739
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Articles

Science, Vol 196, Issue 4290, 655-656
Copyright © 1977 by American Association for the Advancement of Science

articles

H-y antigen: expression in human subjects with the testicular feminization syndrome

GC Koo, SS Wachtel, P Saenger, MI New, H Dosik, AP Amarose, E Dorus, and V Ventruto

Androgen-insensitive subjects with a 46,XY karotype develop as phenotypic females despite presence of testes. The white blood cells of these females type H-Y antigen-positive indicate that expression of the H-Y cell surface component is androgen-independent.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)