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Science 22 April 1977:
Vol. 196. no. 4288, pp. 452 - 454
DOI: 10.1126/science.557837
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Articles

Science, Vol 196, Issue 4288, 452-454
Copyright © 1977 by American Association for the Advancement of Science

articles

Monosodium glutamate admlinistration to the newborn reduces reproductive ability in female and male mice

WJ Pizzi, JE Barnhart, and DJ Fanslow

Monosodium glutamate (MSG) administered during the neonatal period (days 2 to 11) resulted in a sequence of events that were manifested in adulthood. Reproductive dysfunction was seen in both female and male animals. Females treated with MSG had fewer pregnancies and smaller litters, while males treated with MSG showed reduced fertility. The MSG-treated mice showed increased body weight and decreased pituitary, thyroid, ovary, or testis weights.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Testis Structure and Function in a Nongenetic Hyperadipose Rat Model at Prepubertal and Adult Ages.
L. R. Franca, M. O. Suescun, J. R. Miranda, A. Giovambattista, M. Perello, E. Spinedi, and R. S. Calandra (2006)
Endocrinology 147, 1556-1563
   Abstract »    Full Text »    PDF »
alpha-Melanocyte-stimulating hormone: reduction in adult rat brain after monosodium glutamate treatment of neonates.
R. Eskay, M. Brownstein, and R. Long (1979)
Science 205, 827-829
   Abstract »    PDF »


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