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Science 15 April 1977:
Vol. 196. no. 4287, pp. 322 - 323
DOI: 10.1126/science.196.4287.322
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Articles

Alzheimer's Disease, Trisomy 21, and Myeloproliferative Disorders: Associations Suggesting a Genetic Diathesis

LEONARD L. HESTON 1

1 Department of Psychiatry, University of Minnesota, Minneapolis 55455

Relatives of probands with Alzheimer's disease had excessive incidences of trisomy 21 and myeloproliferative disorders. Microtubules are structures that are likely to be affected by a genetic defect causing a predisposition to Alzheimer's disease, trisomy 21 and, possibly, to myeloproliferative disorders.

Submitted on September 20, 1976
Revised on November 9, 1976


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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