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Science 15 April 1977:
Vol. 196. no. 4287, pp. 301 - 302
DOI: 10.1126/science.847471
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Articles

Science, Vol 196, Issue 4287, 301-302
Copyright © 1977 by American Association for the Advancement of Science

articles

Hepatic regeneration and erythropoietin production in the rat

BA Naughton, SM Kaplan, M Roy, AJ Burdowski, AS Gordon, and SJ Piliero

The regenerating liver produces erythropoietin in response to hypoxia. The amounts of erythropoietin produced in animals subjected to hepatectomy are significantly higher than those observed in sham-operated animals. Hepatic erythropoietin production appears to be dependent upon the stage of regeneration with the highest levels being produced during the period of greatest proliferation and increase in liver mass.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
HIF-1: An Oxygen Response System with Special Relevance to the Kidney.
P. Maxwell (2003)
J. Am. Soc. Nephrol. 14, 2712-2722
   Full Text »    PDF »
Suppression of the Human Erythropoietin Gene Expression by the TR2 Orphan Receptor, a Member of the Steroid Receptor Superfamily.
H.-J. Lee, W.-J. Young, C. C.-Y. Shih, and C. Chang (1996)
J. Biol. Chem. 271, 10405-10412
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)