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Science 25 February 1977:
Vol. 195. no. 4280, pp. 789 - 790
DOI: 10.1126/science.836589
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Articles

Science, Vol 195, Issue 4280, 789-790
Copyright © 1977 by American Association for the Advancement of Science

articles

Zinc binding: a difference between human and bovine milk

CD Eckhert, MV Sloan, Duncan JR, and LS Hurley

Gel chromatography indicated that most of the zinc in cow's milk was associated with high-molecular-weight fractions, whereas zinc in human milk was associated with low-molecular-weight fractions. A species difference in zinc-binding ligands may explain why symptoms of the genetic disorder of zinc metabolism, acrodermatitis enteropathica, can be alleviated by feeding human but not cow's milk.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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P.J. Collipp, B. Kuo, M. Castro-Magana, S.Y. Chen, and S. Salvatore (1983)
Clinical Pediatrics 22, 512-513
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Acquired Zinc Deficiency in a Breast-fed Premature Infant.
T. J. Connors, D. B. Czarnecki, and M. I. Haskett (1983)
Arch Dermatol 119, 319-321
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Acute Zinc Deficiency in a Premature Infant After Bowel Resection and Intravenous Alimentation.
V. C. HERSON, A. F. PHILIPPS, and A. ZIMMERMAN (1981)
Arch Pediatr Adolesc Med 135, 968-969
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Copper Ligands in Human Milk: A Vehicle for Copper Supplementation in the Treatment of Menkes' Disease?.
B. LoNNERDAL, C. L. KEEN, B. HOFFMAN, and L. S. HURLEY (1980)
Arch Pediatr Adolesc Med 134, 802-803
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Trace Elements in the Fetus and Young Infant: I. Zinc.
J. C. L. Shaw (1979)
Arch Pediatr Adolesc Med 133, 1260-1268
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Zinc deficiency in murine milk underlies expression of the lethal milk (lm) mutation.
J. Piletz and R. Ganschow (1978)
Science 199, 181-183
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