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Science 25 February 1977:
Vol. 195. no. 4280, pp. 787 - 789
DOI: 10.1126/science.299957
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Articles

Science, Vol 195, Issue 4280, 787-789
Copyright © 1977 by American Association for the Advancement of Science

articles

Ribavirin: efficacy in the treatment of murine autoimmune disease

LW Klassen, DR Budman, GW Williams, AD Steinberg, and NL Gerber

Ribavirin, a drug with known antiviral activity, was given to mice with established lupus nephritis. Ribavirin was effective in prolonging survival, reducing the titer of antibodies to DNA, and reversing proteinuria. Other antiviral agents were not effective in the dosages used.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
(S)-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral Activity.
E. DE CLERCQ, J. DESCAMPS, P. DE SOMER, and A. HOLYacute (1978)
Science 200, 563-565
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Science. ISSN 0036-8075 (print), 1095-9203 (online)