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Science 11 February 1977:
Vol. 195. no. 4278, pp. 589 - 591
DOI: 10.1126/science.835016
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Articles

Science, Vol 195, Issue 4278, 589-591
Copyright © 1977 by American Association for the Advancement of Science

articles

Intravenous self-feeding: long-term regulation of energy balance in rats

S Nicolaidis and N Rowland

Rats learned to press a lever for intravenous self-injection of liquid diet during periods of several weeks when oral food was not available. The intakes were low but regulated, and were sufficient to balance energy expenditures at low body weight. Systemic receptors alone are thus adequate to motivate feeding behavior and meter the caloric yield of the intravenous injections.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)