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Science 11 February 1977:
Vol. 195. no. 4278, pp. 582 - 584
DOI: 10.1126/science.319532
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Articles

Science, Vol 195, Issue 4278, 582-584
Copyright © 1977 by American Association for the Advancement of Science

articles

Lithium: effects on subjective functioning and morphine-induced euphoria

DR Jasinski, JG Nutt, CA Haertzen, JD Griffith, and WE Bunney

The therapeutic usefulness of lithium in decreasing the euphoria and other symptoms associated with manic behavior and the hypothesis of a common final mechanism for elevations in mood have led to speculation that lithium may block the euphoria induced by drugs of abuse. In this study, lithium alone was antieuphoric in drug-free opiate addicts and, further, did not block morphine-induced euphoria.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Possible involvement of {micro}-opioid receptors in effect of lithium on inhibitory avoidance response in mice.
M-R. Zarrindast, A. Lahmi, and S. Ahamadi (2008)
J Psychopharmacol 22, 865-871
   Abstract »    PDF »
The Switch Process in Manic-Depressive Psychosis.
W. E. BUNNEY Jr., T. R. WEHR, J. C. GILLIN, R. M. POST, F. K. GOODWIN, and D. P. van KAMMEN (1977)
Ann Intern Med 87, 319-335
   Abstract »    PDF »


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